Heart Disease in Women: The Myths and the Truth
“Know Your Numbers”
You will find six health conditions known
to increase the risk for CAD listed below.
All of these conditions are modifiable,
which means that they can be controlled.
You can minimize your risk for CAD by
identifying your personal risk factors and
take action to control these risks. Your
doctor will help you design a treatment
plan tailored to meet your needs.
- High Blood Cholesterol
- High Blood Pressure
- Obesity or Overweight
- Physical Inactivity
- Diabetes
- Smoking
The American Heart Association recommends very specific treatment goals ... and that’s where the saying “know your numbers” comes into play. Because each of these risk factors can be measured by using blood tests or other methods, it will be easy for you to determine if your treatment plan is working. All you have to do is compare your “numbers,” or the results of these tests, to your goal “numbers”.
High Blood Cholesterol
What is cholesterol?
Cholesterol is a type of fat (lipid) and is an
essential nutrient your body needs for many
important functions, such as producing new cells.
If you eat too many foods high in saturated fat
and cholesterol or you have an inherited condition,
the cholesterol levels in your blood may
climb to unhealthy levels. This increases your
risk for developing atherosclerosis (hardening
of the arteries) in the arteries supplying blood
to the heart, brain and legs, and can lead to lifethreatening
illnesses, such as heart attack or stroke.
Are cholesterol and triglycerides the
same thing?
Cholesterol travels through your blood attached
to a protein. This cholesterol-protein package
is called a lipoprotein. Depending on how much
protein there is in relation to fat, lipoproteins
are classified as:
- high density (HDL – good cholesterol, mostly protein with only a small amount of fat),
- low density (LDL – bad cholesterol, mostly fat with only a small amount of protein), or
- very low density (VLDL – similar to LDL cholesterol in that it contains mostly fat and not much protein).
Triglycerides are a type of fat carried in the blood by very low-density lipoproteins (VLDL). Only a small amount of triglycerides is normally found in the blood; most are stored in fat tissue. Women tend to have higher triglyceride levels than men. Cholesterol and triglyceride levels tend to rise with age and obesity. Many people with heart disease have high triglyceride levels in their blood, called hypertriglyceridemia. High triglycerides may not directly cause atherosclerosis but can be associated with health conditions that hasten the process. High triglyceride levels may result from other diseases such as untreated diabetes mellitus. People with high triglycerides often have high total cholesterol, high LDL cholesterol and low HDL cholesterol level.
I have high cholesterol but I don’t
understand what the numbers mean.
When distinguishing cholesterol numbers, you want
to know levels of the following: 1) total cholesterol,
2) LDL (low-density lipoproteins), 3) HDL (highdensity
lipoproteins) and 4) triglycerides. When
you state you have “high cholesterol”, you want to
identify which one of these levels is high.
1) Total cholesterol is a measure of the total amount of cholesterol in the blood. Less than 200mg/dL is desirable.
2) LDL, the “bad” cholesterol, is the main source of cholesterol buildup and blockage in the arteries. Levels of 70-100 mg/dL are optimal, especially if you have a diagnosis of CAD or stroke.
3) HDL, the “good” cholesterol, helps keep cholesterol from building up in the arteries and protects against heart disease, so higher numbers are better. A level less than 40 mg/dL is considered a major risk factor for heart disease. Having an HDL level of 60 mg/dL or more helps to reduce heart disease risk and is the desired level.
4) Triglycerides are another type of fat and if elevated can also increase your heart disease risk.Triglyceride levels are considered borderline if between 150 and 199 mg/dL or high if greater than 200 mg/dL.The desired level is less than 150 mg/dL.
In summary, it is important to know your cholesterol numbers because lowering cholesterol reduces your chance of developing heart disease.
High Blood Pressure
What is blood pressure?
Blood pressure is the amount of force exerted
by the blood against the walls of the arteries.This
pressure is produced by the beating of the heart
to maintain adequate blood flow to other parts
of the body. When the arteries are narrowed or
damaged, they make it harder for blood to flow
and the blood pressure will rise. When high
blood pressure continues
untreated, the heart becomes
strained and blood vessels can
become damaged. High blood
pressure is a major risk factor
for stroke, heart attack or
kidney failure.
My blood pressure reading
is 130/80. What do
these numbers mean?
Blood pressure is measured in
two numbers – the top number
is the systolic reading, which
measures the pressure generated
with each heartbeat. The
bottom number is the diastolic
reading, which measures the pressure when your
heart is resting between beats. The blood pressure
readings listed below will help you interpret your
blood pressure results.
- Normal (ideal): Lower than 120/80
- Prehypertension: Between 120/80 and 139/89
- Hypertension Stage I: Between 140/90 and 160/100
- Hypertension Stage II: Above 160/100
Are women at higher risk of developing
high blood pressure?
Women are particularly at risk of developing high
blood pressure if they are using birth control pills
(especially in combination with cigarette smoking),
during pregnancy, if they are overweight, after
menopause, if they are African American, or if they
have a family history of high blood pressure.
As
women age, they have substantially increased risk
for hypertension.
My blood pressure is 133/84 and I am a
chain smoker. Am I more at risk of getting
high blood pressure?
Nicotine, found in tobacco of any form, will
temporarily increase the blood pressure and the
heart rate with each use. It also causes constriction
in the arteries of the arms and legs, which
will increase an individual's blood pressure. In
time, smoking combined with other risk factors
significantly increases the chance of developing
coronary artery disease.
I am 58 years old and always had blood
pressure readings of 110/70. For the
past two years, my automated blood
pressure readings at the grocery store
have been fluctuating – 150/73, 145/76,
135/76, the highest being 156/76. Do I
have high blood pressure?
You will be diagnosed with hypertension if your
blood pressure measurements are above 140/90
mm Hg on three or more separate occasions.
They are usually measured one to two weeks
apart. Except in very severe cases, the diagnosis
is not based on a single measurement. High blood
pressure screening tests and programs vary widely
in reliability. Results from automated blood pressure
testing, such as you might do at a grocery
store or pharmacy, may not be accurate. Any high
blood pressure measurement discovered during a
blood pressure screening program needs to be
confirmed by a health professional.
I do not have any symptoms from
high blood pressure. Is it necessary
to continue treatment?
High blood pressure can damage your arteries,
heart and kidneys, and lead to atherosclerosis
and stroke. Hypertension is called a “silent killer”
because it does not cause symptoms unless it is
severely high and, without your knowing it, causes
major organ damage if not treated.
I am 58 years old and always had blood
pressure readings of 110/70. For the
past two years, my automated blood
pressure readings at the grocery store
have been fluctuating – 150/73, 145/76,
135/76, the highest being 156/76. Do I
have high blood pressure?
You will be diagnosed with hypertension if your
blood pressure measurements are above 140/90
mm Hg on three or more separate occasions.
They are usually measured one to two weeks
apart. Except in very severe cases, the diagnosis
is not based on a single measurement. High blood
pressure screening tests and programs vary widely
in reliability. Results from automated blood pressure
testing, such as you might do at a grocery
store or pharmacy, may not be accurate. Any high
blood pressure measurement discovered during a
blood pressure screening program needs to be
confirmed by a health professional.
I do not have any symptoms from
high blood pressure. Is it necessary
to continue treatment?
High blood pressure can damage your arteries,
heart and kidneys, and lead to atherosclerosis
and stroke. Hypertension is called a “silent killer”
because it does not cause symptoms unless it is
severely high and, without your knowing it, causes
major organ damage if not treated.
Obesity or Overweight
I am 40 lbs overweight. My weight is
mostly around my abdomen. What is
my risk of developing CAD?
Women with excess body fat are at higher risk
of heart disease, even if they don’t have other risk
factors. The exact risk is still a matter of some
debate, but it is known that increased weight
increases your chances of developing high blood
pressure, diabetes and high cholesterol, all major
risk factors for CAD. Fat deposits, especially
around the abdomen, are an important independent
risk factor for developing coronary artery
disease. The ideal waist circumference for women
is 35 inches or less.
An additional method to determine if you are at your goal weight is to use the body mass index, or BMI. The BMI is a calculation that considers the relationship between a person’s height, weight and body fat. The desired BMI is 18.5- 25.
To determine your BMI, use calculator on this page.
Physical Inactivity
I am 63 years old and have high cholesterol
and high blood pressure. My doctor
said I should exercise but I’ve never done
that in my life. Will it really help?
Lack of exercise is a risk factor for developing
coronary artery disease (CAD). Lack of exercise
can indirectly increase the risk of CAD because it
also increases the risk of diabetes and high blood
pressure. Regular exercise can help reduce your
risk of CAD by helping you control cholesterol
and blood pressure, regulate blood sugar (important
for people with diabetes), and lose weight.
Regular exercise is essential not only for preventing
CAD but also for improving your overall
cardiovascular health. Check with your doctor
first before starting an exercise program if you
have diagnosed CAD, have been sedentary for a
long period of time, or have other heart, lung or
metabolic diseases, such as diabetes.
Diabetes
Is heart disease directly related to
diabetes? If so, in what way?
People with diabetes are more prone to heart
disease and stroke. Long-term complications from
diabetes develop because of persistent high blood
sugar levels and progression of atherosclerosis in
arteries throughout the body including arteries to
the eyes, kidneys, heart, brain and legs. Diabetes
damages the lining of blood vessels, causing them
to become clogged with plaque, which is made
up of cholesterol, white blood cells, calcium and
other substances that collect under the inner
lining of an artery. This damage narrows the vessels,
decreasing the blood supply, which eventually
causes injury to the affected area. It also increases
the pressure in the blood vessels, resulting in high
blood pressure. When blood vessels that supply
the brain and heart are affected, a heart attack or
stroke may occur.About three-quarters of people
with diabetes die of some form of heart or blood
vessel disease. A person with diabetes has the
exact same risk for a heart attack as a person of
the same age who has already had a heart attack.
People with diabetes who experience a heart
attack have an unusually high death rate
immediately or in the long term.
How young is too young for people with
diabetes to develop heart disease?
There is no specific timeframe for developing
CAD if you have diabetes. In many circumstances,
people who are newly diagnosed with Type 2
diabetes have had abnormally high blood sugars
long before the diagnosis was made. Therefore, it
is difficult to know exactly how long the heart has
been exposed to the effects of diabetes. However,
diabetes is frequently associated with other risk
factors. Rather than focus on a person’s age at
time of diagnosis, it is more important to keep the
blood sugar under good control or modify other
cardiac risk factors, such as quitting smoking,
increasing activity, and working to get weight,
blood pressure and cholesterol to goal levels.
Are women with diabetes at higher risk
of heart disease?
Diabetes eliminates any survival advantage
that a woman has over a man of the same age.
A woman with diabetes has the same risk of
dying from heart disease as a man her same age.
Women with diabetes have 2-4 times higher risk
of heart disease compared to women without diabetes.
As women age, diabetes is more common
and diabetes affects more women than men over
the age of 60 years. If a woman has diabetes,
she should aim to achieve near-normal fasting
plasma glucose (blood sugar) of less than 100
mg/dL and near normal HbA1c of less than
percent. (Hemoglobin A1c measures average
blood sugar over the course of three months
and a physician can order this test.)
Smoking
I have been smoking a pack of
cigarettes daily for the last five years.
Does smoking affect the heart?
Cigarette smoking is one of the most powerful
risk factors for CAD in women. It is associated
with 50% of all cardiovascular events in women.
The incidence of a heart attack increases sixfold
in women vs. threefold in men who smoke.
When combined with other factors such as oral
contraceptive use, it greatly increases the risk.
In addition, smoking increases the blood pressure,
decreases exercise tolerance, increases the
tendency for the blood to clot, increases LDL
cholesterol and decreases HDL cholesterol.
I recently quit smoking. How long will it
take to reduce my risk of heart disease
to that of a non-smoker?
The risk of CAD and stroke begins to drop
immediately after quitting smoking. It becomes
half after one year without smoking and continues
to decline thereafter to a nonsmoker’s risk.
My husband is a smoker. Am I at
increased risk of heart disease due to
secondhand smoking?
Constant exposure to other people’s tobacco
smoke, called passive smoke, does increase your
risk for CAD. After spending just 30 minutes in a
smoky room, oxygen in the blood decreases, blood
pressure rises and blood is more likely to clot.

