|
August 1, 2000
News this month
The role of clinical breast exams
Clinical breast exams
(CBEs) are at best forgettable for the woman involved and at worst
slightly embarrassing. But are they of value in detecting breast
cancer? Yes, according to new data from the National Breast and
Cervical Cancer Early Detection program. The study, published in
the June 20 issue of the Journal of the National Cancer Institute,
found that manual exams detected very small cancers and sometimes
even found cancers that were not picked up by mammogram. It should
be stressed that mammogram, a detailed X-ray of the breast, is still
the best way to detect breast cancer an average of 1.7 years before
a woman can feel the lump. Mammography also locates cancers too
small to be felt during a clinical breast examination.
Manual exams detected very small cancers and sometimes
even found cancers that were not picked up by mammogram.
Determining the value of CBEs
Since 1991, the National Breast and Cervical Cancer Early Detection
program has provided free mammograms, Pap smears and clinical breast
exams to more than 2.2 million low income women across the country.
This program has provided useful data for a number of studies, but
to date very little has been published on the value of clinical breast
exams. The researchers, led by Janet Bobo of the U.S. Centers for
Disease Control and Prevention, wanted to find out if CBEs done in
the community setting were as valuable as CBEs done during clinical
trials.
Results from more than 750,000 women
The researchers analyzed data collected from 752,081 CBEs performed
from 1995 through 1998. In all, the researchers determined that about
7 percent of all CBEs were suspicious for cancer. Overall, five cancers
were detected per 1,000 examinations. They also found that the values
observed for sensitivity (58.8 %) and specificity for cancer (93.4
%) were comparable to those reported for the CBE component of clinical
trials. That meant that the exams being done in the community setting
were turning up results similar to those done during clinical trials,
which was good news.
CBEs were detecting cancers in a small percentage
of women who had had normal mammograms. However,
CBEs did not
come close to detecting all the cancers.
Finding cancers after normal mammograms
What was very interesting was that the CBEs were detecting cancers
in a small percentage (seven cancers per 1,000 records) of women who
had had normal mammograms. However, its important to note that
the CBEs did not come close to detecting all the cancers.
When the CBE was normal but the mammography was abnormal, the rate
of detection was 42 cancers per 1,000 records. When both CBE and mammography
results were abnormal, the rate of detection was 170.3 cancers per
1,000 records. Cancer detection could not be attributed entirely to
CBE or mammography on about a third of this last group because the
tests were performed on the same day.
Breast cancer screening schedule
Women under age 40 should perform monthly breast self exams and
receive an annual breast exam by a physician. In addition to self
exams and clinical exams, women age 40 to 49 should have mammography
every one to two years and an annual mammography from age 50 and older,
according to the National Cancer Institute. The researchers concluded
that community-based CBEs detected breast cancers as effectively as
CBEs performed in clinical trials and might make slight improvements
in early detection programs.
JAMA study sheds light on CBEs
A study published in the Journal of the American Medical Association
last fall suggested that properly performed CBEs can detect at least
50 percent of cancers where symptoms are not yet present and may help
save lives in women screened. However, they also noted there was wide
variation among physicians in how they performed CBEs. The study recommended
that a clinical breast exam take at least three minutes per side and
offered a detailed description of how the exam should be done.
Physician Referral Online
A free and confidential service
of Yale-New Haven Hospital.
Physician Referral Online
Using your own criteria, you can request information from a database
of 900 area physicians who have registered to participate.
Request an appointment
We would be happy to assist you in scheduling an appointment with
a member of the hospital's medical staff. Use the link above or
call:
203-688-2000
or toll free
1-888-700-6543
to talk with a referral coordinator.
|

|

Why women need clinical breast exams
When discussing
breast cancer detection, I first want to make sure all women know
that mammography is still our best screening tool. But because mammography
is not perfect, there is still great value in performing monthly
breast examinations, as well as going for an annual clinical breast
exam (CBE) with your primary care provider. The question of how
valuable clinical breast exams are in saving lives has generated
some controversy. Im of the mindset that I want to do everything
possible to detect breast cancer, even if there is doubt remaining
in some peoples minds.
Clinical breast exams or self exams are particularly valuable in
detecting types of breast cancers that usually do not show up on
mammograms. These types of cancers do not tend to calcify (form
round, hard balls) like most breast cancers so they dont show
up on mammogram.
"Mammography is still our best screening tool. But
there
is still great value in performing monthly breast examinations, as
well as going for an annual clinical breast exam (CBE)
"
Dont forget self exams
An example is invasive lobular cancer. Ive treated women
with this type of cancer who needed mastectomieseven though
they had regular mammogramsbecause they were not doing self
exams. Any diffuse changes you find should be brought to your doctors
attention right away. By diffuse I mean a generalized thickening or
marked change in the texture of the breast that does not go away.
This can change the way the breast lookseither you see dimpling
or retraction or a difference in appearance between the two breasts.
Who should perform CBEs?
As a surgeon, I do a lot of clinical breast exams, but ideally a woman
should be having this done by her regular primary care provider or
gynecologist. Doctors learn how to perform breast self exams during
their training in medical school. I review the procedure with our
own medical students. The JAMA study suggests that a CBE take five
to 10 minutes. In reality, I think thats too long and is not
practical. Instead, I recommend our med students come up with a shorter
technique they can perform on everyone.
Self exams
Its easier to feel lumps in the breast after menopause because
of changes in the breast itself. The absence of estrogen causes the
amount of ductal tissue to diminish and it is replaced by fat. Women
who have fibrocystic breasts are harder to exam because they naturally
have lumpier breasts. But thats why its doubly important
for these women to do self exams so that they know whats normal
and what is not. If a patient tells me she feels a change, she is
the experteven more so than another doctor.
"If you find something,
remember the vast majority of
lumps are not cancerous."
Performing a clinical breast exam on a patient is an excellent time
for me to teach the patient how to perform a self exam. I tell women
that feeling a lump has a three-dimensional aspect to it. Cancers
tend to have rough edgesnot smooth edges like an M&M candy
does. The menstrual cycle also influences how the breasts feel. The
best time to examine the breasts is about a week after your period
ends. If you are past menopause, try to come up with one date each
month that you always do the exam. If you find something, try not
to panic but remember the vast majority of lumps are not cancerous.
The take-home message is that all of these toolsmammography,
clinical breast exams and self examshave their own important
role in detecting breast cancer. Use everything youve gotfrom
shower cards that show how to do a breast self exam to a buddy system
of calling a friend every month as a reminder.
Dr. Ward is
director of the Yale Comprehensive Breast Care Center and is a surgical
oncologist affiliated with Yale-New Haven Hospital.
Yale-New Haven was recognized this year by U.S. News & World Report for its cancer services.
|