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March 26, 2003
News this month
Sleep imbalance linked to heart disease
Researchers at Brigham and Womens Hospital in Boston found
that women who are chronically sleep deprived or who routinely sleep
more than the usual eight hours seriously increase their risk of
developing heart disease. Sleep shouldnt really be considered
a luxury, according to the studys principal author, Dr. Najib
Ayas. Sleep is probably one of the pillars to a healthy lifestyle.
Too little sleep puts stress on the body.
Women who are chronically sleep deprived
or who routinely sleep more than the usual eight hours seriously
increase their risk of developing heart disease.
The research focused on 71,617 women between 40 and 65 years of
age who participated in the ongoing Nurses Health Study. None
of the women reported having heart disease at the start of the study
in 1986. The women were polled on their sleeping habits and were
followed for a decade to see who developed heart problems. Between
1986 and 1996, the group experienced 934 heart attacks, including
271 fatal and 663 nonfatal events.
Solid eightthe best bet
After accounting for other factors that might raise the risk of
heart disease in people who sleep too little or too much, such as
snoring, smoking and weight, the scientists still found that how
long the women slept mattered.
Women who reported sleeping 5 hours
or less per night were 45 % more likely to have heart problems.
Compared with women who slept eight hours, women who reported sleeping
five hours or less per night were 45 percent more likely to have
heart problems. Women who slept six hours per night had an 18 percent
increased risk and seven hours of sleep put the women at a 9 percent
higher risk.
And too much of a good thing may not be the best option. Women
in the study who slept nine hours or more were 38 percent more likely
to experience heart problems than women who slept eight hours. Dr.
Ayas says he finds it hard to believe, however, that sleeping too
much is harmful. He suspects some unaccounted factors related to
sleeping long hours, such as obstructive sleep apnea, may explain
the findings.
Men have to pay attention to their sleep patterns, too. While
this study involved women, theres no physiological reason
why these findings should not apply to men too, according to Dr.
Ayas. While cautioning that the study is preliminary, Dr. Ayas acknowledged
that the findings have prompted him to increase his sleep time from
six hours to seven or eight hours a night.
Shortened sleep can induce changes in the body that would promote
high blood pressure,
obesity
and diabetes. Jim
Walsh, MD
Prior research collaborates findings
Previous research shows even short-term sleep deprivation can adversely
affect heart disease risk factors. According to Dr. Jim Walsh who
serves as president of the National Sleep Foundation (NSF), shortened
sleep can induce changes in the body that would promote high blood
pressure,
obesity
and diabetes. In the long run, I think
we will find an association between short sleep and some major medical
illnesses. The new study, published in the Archives of Internal
Medicine, is one of the first to look at the health effects
of too-little sleep over a long period of time.
This new study provides an important look at the relationship
between sleep and cardiovascular disease in women, an area of research
that has not received much attention, the NSF said in a statement.
Sleep Foundation poll
According to the NSFs 2002 Sleep in America poll,
the overall sleep habits of Americas adults have remained
consistent since the first Sleep in America poll in 1998, but the
2002 results show what may be a trend towards less sleep.
- Fewer adults appear to be getting eight
or more hours of sleep each night in the 2002 poll compared to
one year ago (38% vs. 30%)
- Overall, 24% report that they get
less than the minimum amount of sleep they believe they need to
not feel sleepy the next day.
Women average seven hours of sleep on weeknights, (compared to
6.7 hrs/night for men). They are much more likely to report having
symptoms of insomnia than men (63% vs. 54%) and frequent daytime
sleepiness (20% vs. 13%).
In addition, more than one quarter of the women polled said they
get less sleep than they need to be fully alert the next day.
In light of these and other similar findings, NSF urges patients
and physicians to give greater attention to sleep. Patients should
discuss with their doctors the quantity and quality of their sleep
and whether they experience daytime sleepiness, insomnia, snoring,
pauses in breathing, leg movements or other disruptions during the
night that can affect their quality of life during the day and could
potentially impact their long-term health status.
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Request an appointment
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a member of the hospital's medical staff. Use the link above or
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Good sleep habits important for continuing
health
There have been several studies linking both too little and
too much sleep with health problems. This latest research, which
is part of the well-known Nurses Health Study, is a very
well-designed investigation of more than 71,000 women over 10
years.
Chronic sleep deprivation [may]
result in an increase of stress hormones circulating in the body.
Stress hormones to blame?
What is the reason for the correlation between poor sleep behavior
and heart disease? We dont know for sure, but there is much
evidence to suggest that chronic sleep deprivation results in
an increase of stress hormones circulating in the body, cortisol,
in particular.
Cortisol is released in the body during physical and psychological
stressed or agitated states. It is very useful in mobilizing individuals
to cope with dangerous or threatening conditions in the short
term, but when stress hormones are elevated over long periods
of time, they can wreak havoc on the body. In fact, chronically
elevated cortisol levels are associated with high blood pressure
and glucose intolerance, which is a precursor of diabetes, a major
risk factor for the development of heart disease.
The study also indicates that sleeping more than nine hours
on a routine basis is also related to a higher incidence of heart
disease. Here, the association is probably related to the presence
of underlying diseases such as depression, chronic pulmonary disease
and sleep apneaÖall of which can interfere with the quality of
sleep and people may compensate by increasing the amount of time
they spend sleeping.
An eight-hour sleep time [is]
optimal
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Sleep patterns
Over the course of human evolution, our need for sleep hasnt
varied much. In the last 100 years, as industrialization has intensified,
we have experienced a decline of about an hour and a half of sleep
each night. The research studies support an eight-hour sleep time
as optimal, but some people can still function with a little less
time; six-and-a-half to seven hours is sufficient for some people.
Abrupt changes in sleep habits can be distressing, however,
as anyone who has experienced jet lag can attest. Our bodies work
on a 24-hour cycle, called “circadian rhythms,” which
can be measured by the rise and fall of body temperature, the
presence of certain hormones in our blood and other biological
conditions. All of these are influenced by exposure to sunlight
and help determine when we sleep and when we wake.
When traveling to new time zones, our circadian rhythms are
slow to adjust and remain on their original biological schedule
for two or three days. This results in our bodies telling us it
is time to sleep, when its actually the middle of the afternoon,
or it makes us want to stay awake when it is late at night.
By age 60 or 70, many adults
experience a steady decrease in the proportion of time spent in
deep, so-called ‘delta’ sleep.
Sleep patterns change as we age. Babies and young children nap
frequently during the day, and even as we mature, our bodies experience
a slowdown in the afternoon hours. Many adults benefit from a
short, 30-minute nap at midday. Many cultures accommodate this
slower phase in our daily cycle with afternoon rest periods. As
we age, the quality of our sleep changes. Middle-aged and elderly
people tend to spend less time in deeper sleep than younger people.
By age 60 or 70, many adults experience a steady decrease in the
proportion of time spent in deep, so-called ‘delta’
sleep.
Insomnia
Insomnia can have many causes. Some people have trouble falling
to sleep; others fall asleep easily but have trouble staying asleep.
The latter kind of insomnia is more often related to underlying
medical conditions such as heart failure, chronic obstructive
pulmonary disease, movement disorders and depression.
If you are experiencing chronic insomnia, Its a good idea
to check with your doctor to determine if your insomnia is a byproduct
of another condition. Some medications can also interfere with
sleep. Let your doctor know if you are experiencing sleeping problems
after beginning a new medication.
Cultivate good sleeping habits
- Get up about the same time every day—even
on weekends. Sleeping in on Sunday morning can interfere with
a restful sleep Sunday night and impair your effectiveness on
Monday.
- Exercise regularly, but if you exercise
vigorously, do so at least five to six hours before bedtime.
- Cut down on anything containing caffeine,
such as coffee, tea, colas and chocolate, especially later in
the day.
- Sleep on a comfortable bed.
- Dont smoke. Nicotine is a more
powerful stimulant than caffeine.
- Drink only in moderation. Do not drink
alcohol within several hours of bedtime.
- Strive for quality over quantity. Light
dozing is no substitute for a solid, restful sleep.
- Dont take your worries to bed.
Learn to set aside anxieties for times when you can do something
constructive to address them.
- Dont go to sleep stuffed or hungry.
Snacks such as bananas, warm milk and cheese may help you fall
asleep.
- Develop a relaxing sleep ritual such
as reading or listening to music. Give yourself 30 to 60 minutes
to wind down from the activity of the day and cue your body
to settle down for the night
People who suffer from insomnia that lasts for more than a few
days should consult a physician so that the underlying cause can
be identified, if possible, then treated.
Dr. Mohsenin is the medical director of the Yale Center for
Sleep Medicine and an associate professor of medicine at the Yale
University School of Medicine.
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