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March 28, 2005
News this month
Earlier epidurals offer pain relief without increasing C-sections
Although about 60 percent of American women in labor currently
receive epidurals, there has been considerable controversy about
when it is safe to administer the pain-relieving medication, particularly
for first-time mothers.
There has been considerable controversy about when it is safe to administer pain-relieving epidurals.
Studies conducted in the 1990s indicated that epidurals given
before a woman's cervix was dilated at least four centimetersnearly
halfway to the 10 centimeters needed for a normal deliverycould
lead to longer labors and a higher risk of Caesarean sections.
Many doctors believed that epidurals early in labor could interfere
with uterine contractions and a woman's ability to push.
These physicians administered systemic narcotics for those requesting
pain relief.
Other researchers suggested that the prolonged labors and higher
Caesarean rates associated with those women requesting early
epidurals might be a result not of the epidurals but of very
large babies or babies turned in the wrong direction.
Study shows no negative effects of early epidurals
A study published in the New England Journal of Medicine challenges
the practice of withholding epidurals until advanced labor.
In this study, conducted at Northwestern Memorial Hospital
in Chicago, women given epidurals before the dilation threshold
of four centimeters actually had faster deliveries, better
pain relief and no increased rate of C-sections, compared to
women who received narcotics for pain relief.
In the study, physicians used a low-dose pain relief known as combined
spinal epidural. A small dose of medication is injected
in the spinal fluid and the epidural is later fed through the
same hole into a space farther from the spine.
The C-section rate was statistically a tie between the early epidural group and the narcotic injection group.
In this study, 750 women in early-stage, first-time labor were
divided into two groups. One group received a spinal anesthetic
and the other group received narcotic injections at the first request
for pain relief. At the second request, the women who had received
spinals were given epidural anesthesia; the injection group received
a second narcotics injection. After that time, women who received
narcotics were given epidurals when they reached four centimeters or when they
asked for more pain relief.
In the end, the C-section rate was statistically a tie between
the early epidural group and the narcotic injection group: 17.8
percent vs. 20.7 percent, respectively. The women with spinals
experienced an hour and a half less of labor than the narcotics
group, and they reported much less paintwo vs. six
on a 0-10 scalethan the injection group.
Dr. Cynthia Wong, lead author of the study, said women are often
pressured to delay epidurals and made to feel guilty or weak if
they asked for one too soon in labor. Women say: 'I
must be a wimp. I had to ask for pain medication so early,' Dr.
Wong said. The bottom-line message is that if you're
a first-time mom in early labor and it hurts and you need pain
medicine, by getting this kind of spinal-epidural you're
not at increased risk for a C-section, and there are benefits to
doing it this way.


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Epidural study may relieve anxiety about pain relief
This very well-designed study provides the data that demonstrates what anesthesiologists have long observed among their patients: Epidural pain relief does not negatively affect the outcome of a birth experience for the mother or baby. Our goal is for our patients to safely and healthfully deliver their babies the way they choose to-with or without pain medication or epidural analgesia.
Epidural pain relief does not negatively affect the outcome of a birth experience for the mother or baby.
Not your mother's epidural
Earlier studies
that indicated a higher risk of forcep-assisted deliveries and
C-sections may well have been a result of the kind of medication
used in epidurals that were administered decades ago. The epidurals
we give today bear little resemblance to those. We've adjusted
the type and amount of medication so that women are no longer
rendered totally numb and unable to move after receiving an epidural.
Women can push, and, if they choose, they can get up and walk
around. Our experience indicates most women are exhausted in
labor and would rather rest than walk, but they do have that
option. Women may still feel contractions; patients often report
feeling like they're having menstrual cramps. For those
women who don't want to feel those sensations, we can adjust
the medication appropriately.
Epidurals deliver pain-relieving medicine through a skinny
plastic tube that is threaded into the back, close to spinal
nerves, bypassing the mother's bloodstream. We've
welcomed epidurals as an alternative to systemic pain
medicine that passes through the bloodstream, which can leave
some women feeling nauseated and drowsy. The placement of an
epidural does cause some discomfort, but patients say the discomfort
is well worth the option of having a less painful labor and birth
experience.
We have noticed that women who receive spinal narcotics (analgesia)
very early in laborand that is actually a small percentage
of womenmay become fully dilated more quickly. One theory
is that pain increases the secretion of fight or flight hormones
such as adrenaline, which may slow the laboring process. Once
pain is relieved, the hormone secretions stop and contractions
continue.
Not safe for everyone
Who shouldn't have epidurals? Women who have systemic
infections, bleeding disorders or who are taking anticoagulants
should not be given an epidural because of an increased risk
of an abscess or hematoma. And certainly, any woman who does
not want an epidural for any reason should not be given one.
What I try to communicate to patients is that it's a
good idea to come to the birth experience with few expectations
regarding pain medications. We don't want anyone to feel
as though they've somehow failed because they've
received pain relief. We encourage women to learn as much as
possible about pain relief options before labor since knowing
your options and any associated risks of those options can help
you make the best choice for you.
The good news about this study is that a woman who wants pain
relief can choose an epidural without worrying about negatively
affecting her labor, her health or her baby's health.
Dr. Braveman is an attending obstetrical anesthesiologist at Yale-New Haven Hospital and a professor of anesthesiology and section chief of obstetrical anesthesiology at the Yale University School of Medicine.
For the 13th year in a row, Yale-New Haven
has been highly ranked by U.S. News & World Report for
its programs in gynecology.
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