The Yale Center, which is the model for 27 HHT Centers worldwide, manages 3,000 patients with HHT including primary treatment and follow-up. Daily clinics for patients with vascular malformations, genetic counseling, evaluation and work-up for patients with gastrointestinal bleeding and liver, pulmonary and brain malformations associated with HHT are among the services offered. In addition to teaching within the United States and overseas, the faculty publishes the results of their research regularly in a variety of peer-reviewed journals. Yale founded a non-profit foundation
for HHT in 1991.