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Phone Numbers

Directory assistance
(203) 688-4242

Patient information
(203) 688-4177

Adult emergency
(203) 688-2222

Children's emergency
(203) 688-3333

Admitting
(203) 688-2221

Children's admitting
(203) 688-3331

Psychiatric admitting
(203) 688-9907


Childhood cancers

Brain and central nervous system (spinal cord) cancers

The brain and spinal cord are made up of many different types of cells and tissues. Abnormal growths can occur in a variety of locations in the brain and central nervous system (CNS). It's important to note that not all of these growths are cancerous.

Cancerous tumors of the brain and spinal cord represent the second most common type of cancer affecting children, accounting for 20 percent of all childhood cancers. Progress is being made in treating these cancers, but the outlook for children with these cancers depends on the type of cancer and the stage at which it is diagnosed.

Risk factors
The cause of brain and CNS cancers is not known in the majority of children. Genetic research is yielding more clues about this disease. However, scientists studying the patterns of occurrence have noted that rare cases of brain and spinal cord cancers run in families.

About 20 percent of all brain tumors occur in children younger than 15, usually peaking between five and 10 years old. Slightly more boys than girls are affected.

Symptoms
There are no screening tests available to detect brain or CNS cancers. The location of the cancer influences the child's symptoms. The child may suffer from headaches that are combined with nausea and vomiting, blurred or double vision, dizziness or difficulty in walking. Sometimes these symptoms become worse over time, but in some cases, symptoms may occur more suddenly and be more severe. There may be a delay in diagnosis because many of these symptoms mimic those caused by noncancerous conditions.

Questions to ask your child's doctor

Diagnosis
A medical history and physical exam can help determine if a child needs further evaluation. If a tumor is suspected, imaging tests such as bone X-rays, MRI, CT scans and nuclear scans are used. Needle or open biopsies or spinal taps can then be used to determine if cancer is present and the type of cancer. Sometimes genetic studies can provide more information. Diagnosing cancer


Treatment

Before cancer is treated, it has to be staged. Staging involves finding out where the cancer is located, the extent of the cancer and whether it has spread. The type of cancer will determine treatment.

The cancer team at Yale-New Haven Children's Hospital includes the child's pediatrician as well as specialists (such as pediatric oncologists and neurosurgeons) at the Yale Cancer Center. Once the cancer is staged, the cancer care team will suggest a treatment plan. This is an important decision and it is good to take time and think about all of the choices.

With cancers of the brain and CNS in children, a combination of surgery, radiation and chemotherapy is often used. For some types of tumors, surgery alone is sufficient. Radiation therapy is sometimes delayed or avoided in children age 3 and younger because of potential developmental problems later on. Chemotherapy can cause side effects as well. Be sure to discuss side effects of treatment with the pediatric oncologist before your child begins therapy.

Clinical trials, protocols and research


Learn more

• YNHH Health Library: Brain tumors

 

Last revised: Jan. 9, 2008 (dh)


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