Our Medical Services

Hematology, Oncology and Stem Cell Transplantation

Hematology, oncology and stem cell transplantation is unique in its depth of experience and skill in the latest advances in diagnosing and treating childhood cancer and blood disorders. Our infant, child and young adult patients with cancer are offered the best opportunity for accurate diagnosis and the most effective treatment available.

Hematology, Oncology and Stem Cell Transplantation

Among the top hospitals in the country for pediatric cancer

U.S. News Best Children's Hospitals  oncology 2014Yale-New Haven Children's Hospital has been ranked among the best in the nation in six pediatric subspecialties, including pediatric cancer (#44). The results appeared in the 2015-16 edition of "Best Children's Hospitals," published online by U.S.News & World Report.  

About us

Our dedicated pediatric hematologists and oncologists provide care for children with all forms of cancer and blood diseases, including leukemia, malignant tumors and lymphomas, as well as sickle cell disease, hemophilia, coagulation abnormalities and platelet disorders. Our participation in the Children's Oncology Group studies makes it possible to provide the most current and advanced treatment regimens to children with any form of cancer, common or rare.

Care of our patients and advances in treating pediatric cancer and blood diseases require a team approach. Our multidisciplinary team of physicians in pediatrics, laboratory medicine, surgery, neurosurgery, orthopedics, pathology, therapeutic radiology and diagnostic radiology work together on a case-by-case basis to treat each child.

Our specialized programs

The pediatric neuro-oncology clinic is the only one of its kind in Connecticut dedicated to treating brain tumors. Patients receive care from pediatric oncologists, neurologists, endocrinologists, neurosurgeons, psychologists and social workers, with extensive expertise in treating these types of complex cancers. We participate in national clinical trials and develop trials for more experimental therapies through brain tumor consortiums.

The pediatric blood and marrow transplantation program offers bone marrow, peripheral blood stem cell and cord blood transplants. Children are cared for by a highly trained medical team that understands the application of research-based therapies and the care needed for pediatric patients undergoing transplantation.

Our team of specialists in pediatric hematology manages a wide range of congenital and acquired bleeding and clotting disorders through disease-specific programs. They include:

The pediatric hemostasis and hemophilia clinic is a a federally designated hemophilia treatment center with over 28 years of experience caring for those with hemophilia, von Willebrand disease and rare bleeding disorders. Patients and families have access to a multidisciplinary team of physicians, registered nurses and social workers who treat the whole child throughout their life and works closely with pediatric dentistry and physical therapy when patients need their care.

Pediatric sickle cell and thalassemia diseases are managed by a multidisciplinary team of board-certified pediatric hematologists, nurse practitioners, a psychologist, pediatric pain specialists and social workers who treat and manage sickle cell disease and thalassemia in infants, children and adolescents. The care team works closely with their adult hematology colleagues to ensure a smooth transition from pediatric to adult care.

The pediatric tumor program offers comprehensive care to children with a wide varity of tumors, including bone and soft-tissue sarcomas, liver and kidney tumors, neuroblastoma, retinoblastoma and other rare tumors. Care is delivered by a team of pediatric and radiation oncologists, surgeons, pathologists, nurses and social workers.

The HEROS Clinic for Childhood Cancer Survivors is the first cancer survivor clinic in Connecticut and one of the first in the United States. Established in 2003, the HEROS Clinic provides individualized screening for children, adoloescents and adults for late complications of past chemotherapy, radiation, and surgery. Problems can include hormone deficiencies, decreased heart function, decreased bone mineral density, learning problems the development of new cancers. Fortunately, most late effects can be prevented or improved by early detection.

Patients are eligible for HEROS if they were diagnosed with a cancer condition under the age of 21 and are off-therapy.

The adolescent young adult oncology program is exclusively dedicated to supporting adolescents and young adults, ages 13 and up. Integrating the resources of Yale-New Haven Children’s Hospital and Smilow Cancer Hospital at Yale-New Haven, patients receive coordinated care, including fertility counseling, education, insurance, and social and emotional support.


  • DNA and genome biology and translation cancer therapy
  • Immunology-based and vaccine therapy
  • Interventions for increased quality of life
  • Cutting-edge clinical trials
  • Red blood cell biology

Supportive services

Understanding that children with cancer and blood disorders need more than medical care, we work with patients and their families to help them meet their social, emotional, educational and behavioral needs. Our support services include:

  • Routine psychosocial evaluations for newly diagnosed patients and their families
  • Home visits for the most gravely ill or psychiatrically symptomatic children and their families
  • A school integration program that includes counseling for families and children about their rights to have special services and working with school districts to make appropriate accommodations for students returning to school, including providing special education services, if necessary.
  • Psychoeducation and neuropsychological testing for patients at risk for neurocognitive problems
  • Support groups for siblings
  • Support groups for parents
  • End-of-life support team for terminally ill children

Nicole Graham — A Heroic Recovery


High school student Nicole Graham was diagnosed with leukemia during her junior year and soon found herself in the PICU with life-threatening complications. Her disease is in remission now — she attended her junior prom — and she remembers fondly the care she received at YNHCH, from expert physicians and some very special nurses. 



Retinoblastoma is a rare type of eye cancer that usually develops in early childhood, typically before the age of 5. Yale-New Haven specialists offer novel treatment options, tailored for each patient.