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SCINTIX Biology-Guided Radiation Therapy (BgRT)

Overview

Smilow Cancer Hospital is the first in the Northeast United States - and among the first in the world - to offer SCINTIX® Biology-Guided Radiation Therapy (BgRT) to enhance care for our patients with metastatic cancer.

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Revolutionary radiation therapy

SCINTIX therapy is the first and only radiation therapy that allows each cancer’s unique biology to determine where to deliver radiation, second-by-second, during treatment. SCINTIX therapy can shrink the surrounding area of healthy tissue, so that radiation is precisely delivered to the tumor. By reducing the dose to healthy tissue, patients experience fewer side effects of radiation.

SCINTIX therapy quick facts

  • Uses live signals produced by your tumor to precisely direct radiation treatment.
  • Cleared by the FDA to treat tumors in the lung or bone arising from primary or metastatic cancer.
  • Detects tumors even when they are moving.
  • Delivers treatment in five or fewer visits.
  • Non-surgical procedure; no sedation required.
  • Patients can resume normal activities immediately following treatment.

Who can benefit from SCINTIX?

SCINTIX is FDA-approved for lung or bone cancers. The first step is to determine whether a tumor produces the type and volume of chemical signals that can be targeted using the SCINTIX technology.

What to expect during SCINTIX treatment at Smilow Cancer Hospital?

Pretreatment assessment:

Prior to a SCINTIX treatment, you will come to the Radiation Therapy Department so your radiation oncologist can determine whether your tumor produces significant signals to benefit from BgRT therapy. This information is needed to plan whether BgRT can be used to treat your specific cancer tumor.

  • You will receive an injection of a radiopharmaceutical called fludeoxyglucose (18F-FDG) that allows imaging of your tumors.
  • After 60 minutes, the radiation oncology therapist will position you on the SCINTIX machine to collect the unique live signal information from your tumor (or tumors).
  • No radiation is delivered to you during your pretreatment procedure.

Your treatment plan:

Your Smilow physicians review the SCINTIX data to determine whether and how best to treat your specific cancer. Your plan will be discussed with you and all your questions answered.

Treatment session:

  • You will receive an injection of fludeoxyglucose (18F-FDG) and wait for 60 minutes.
  • The radiation oncology therapist will position you on the SCINTIX machine for treatment.
  • Positron emission tomography (PET) and computed tomography (CT) scans will be taken to ensure nothing has changed that would require your physician to modify your SCINTIX treatment plan.
  • The length of your treatment is based on your biology and specific treatment plan.

RefleXion and SCINTIX are trademarks of RefleXion Medical.

Information for referring providers

New patients are welcome, especially with a referral from a physician who can provide medical history. Patients who call our office will be instructed to work with a referring provider if possible.

To refer a patient, call 203-200-2000.
Referrals can also be made through Epic or EpicCare link.

Yale School of Medicine

Yale New Haven Health is proud to be affiliated with the prestigious Yale University and its highly ranked Yale School of Medicine.