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The Pancreatic Cancer Early Detection Program provides comprehensive risk assessment, education, and screening for patients at increased risk of pancreas cancer. Our multidisciplinary expert team of genetic counselors, nurse practitioners, and physicians work together to create a personalized care plan for each patient. Patients with an increased risk can have a consultative visit at the Pancreas Cancer Early Detection Program.

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Who is at Increased Risk of Pancreatic Cancer?

  • Strong family history of pancreatic cancer: 2 or more family members have a history of pancreatic cancer.
  • Genetic predisposition to pancreatic cancer: Inherited susceptibility secondary to BRCA1, BRCA2, ATM, PALB2, p16/CDKN2A (FAMMM Syndrome), Lynch Syndrome (HNPCC), and Peutz-Jeghers Syndrome (STK11).
  • Hereditary Pancreatitis: Chronic pancreatitis that occurs with genetic predispositions: PRSS1, PRSS2, CTRC, and SPINK1.


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Specialty services are offered at our hospitals and ambulatory sites.

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Digestive Health Center – North Haven

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What to Expect from your Appointment

The Pancreatic Cancer Early Detection Program provides a comprehensive, personalized consultation tailored to the needs of the individual patient. Many patients will meet first with a genetic counselor who will review family history and other risk factors for cancer, explain the role of genetic testing for hereditary cancer syndromes, offer testing (if appropriate), and provide an overall cancer risk assessment. Those patients considered to be at increased risk of pancreas cancer can then choose to consult our Pancreatic Cancer Early Detection Program clinicians. We arrange for appropriate high-risk pancreas cancer screening, either clinically or as a part of a prospective research study [CAPS5 and PanFAM1, PRECEDE, and Pancreatic Cyst Study EA2185]. If needed, we can also assist with arranging consultations with other specialists for a multidisciplinary approach to cancer prevention and surveillance.

Available High-Risk Pancreatic Cancer Surveillance Studies

Multiple research screening studies for patients at increased risk of pancreatic cancer are available including CAPS5 and PanFAM1, PRECEDE, and Pancreatic Cyst Study EA2185.

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Yale School of Medicine

Yale New Haven Health is proud to be affiliated with the prestigious Yale University and its highly ranked Yale School of Medicine.